Dr. Joshua Muli Mutiso

Dr-Joshua-Muli

Position: Lecturer
Department: Zoological Sciences
Contact Address: P.O. Box 43844-00100, Nairobi, Kenya
Email: This email address is being protected from spambots. You need JavaScript enabled to view it. , This email address is being protected from spambots. You need JavaScript enabled to view it.
Area of Specialization:Immunology

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 Publications

  • Laban LT, Anjili CO, Mutiso JM, Ingonga J, Kiige SG, Ngedzo MM, Gicheru MM. Experimental therapeutic studies of Solanum aculeastrum Dunal. on Leishmania major infection in BALB/c mice. Iranian Journal of Basic Medical Sciences 18: 64-71.
  • Kiige SG, Mutiso JM, Laban LT, Khayeka-Wandabwa C, Anjili CO, Ingonga J, Gicheru MM. (2014). F1 Cross-Breed Between Susceptible BALB/c and Resistant Swiss mice Infected with Leishmania major Exhibit an Intermediate Phenotype for Lesion Sizes and Type 1 Cytokines but Show Low Level of Total IgG Antibodies. Scandinavian Journal of Immunology 79: 283–291.
  • Mutiso JM, Macharia JC, Gicheru MM, Ozwara H. (2013). Immunology of leishmaniasis. Science Parasitology 14(2):51-61.
  • Mutiso JM, Macharia JC, Kiio MN, Mucheru PM, Onkoba WN, Maloba FC, Gicheru MM. (2013). Leishmania parasite specific CD4+ synergizes and correlates positively with CD8+ T cells in the production of gamma interferon following immunization of the vervet monkey (Chlorocebus aethiops) model. Science Parasitology 14(1):7-19.
  • Mutiso JM, Macharia JC, Kiio MN, Ichagichu JM, Rikoi H, Gicheru MM (2013) Development of Leishmania vaccines: predicting the future from past and present experience. Journal of Biomedical Research 27(2): 85-102.
  • Mutiso JM, Macharia JC, Taracha E, Gicheru MM (2012) Immunization with Leishmania vaccine-Alum-BCG and montanide ISA 720 adjuvants induces low-grade type 2 cytokines and high levels of IgG2 subclass antibodies in the vervet monkey (Chlorocebus aethiops) model. Scandinavian Journal of Immunology 76: 471-477.
  • Mutiso JM, Macharia JC, Taracha E, Gicheru MM (2012) Leishmania donovani whole cell antigen delivered with adjuvants protects against visceral leishmaniasis in vervet monkeys (Chlorocebus aethiops). Journal of Biomedical Research 26(1):8-16.
  • Mutiso JM, Macharia JC, Taracha E, Wafula K, Rikoi H, Gicheru MM (2012) Safety and skin delayed-type hypersensitivity response in vervet monkeys immunized with Leishmania donovani sonicate antigen delivered with adjuvants. Revista do Instituto de Medicina Tropical de São Paulo 54(1):37-41.
  • Mutiso JM, Macharia JC, Barasa M, Taracha E, Bbourdichon AJ, Gicheru MM (2011) In vitro and in vivo antileishmanial efficacy of a combination therapy of diminazene and artesunate against Leishmania donovani in BALB/c mice. Revista do Instituto de Medicina Tropical de São Paulo 53(3):129-132.
  • Mutiso JM, Macharia JC, Mutisya RM, Taracha E (2010) Subcutaneous immunization against Leishmania major infection in mice: Efficacy of formalin-killed promastigotes combined with adjuvants. Revista do Instituto de Medicina Tropical de São Paulo 52(2):95-100.
  • Mutiso JM, Macharia JC, Kariuki TM, Gicheru MM (2009) Montanide ISA 720 is more effective than BCG as an adjuvant for Leishmania killed vaccine in BALB/c mice. International Journal of Integrative Biology 7(2): 107-116.
  • Mutiso JM, Macharia JC, Gicheru MM (2010) A review of adjuvants for Leishmania vaccine candidates. Journal of Biomedical Research 24(1): 16-25.
  • Barasa M, Mwangi I, Mutiso JM, Kagasi AE, Ozwara SH, Gicheru MM (2010) Plasmodium knowlesi H strain pregnancy malaria immune responses in Olive baboons (Papio anubis). International Journal of Integrative Biology 10(1): 54-58.

Research

  • Science, Technology and Innovation Grant Ref: NCST/5/003/CALL2/266, 2010 National Council for Science and Technology (NCST), Government of Kenya - Vaccine Development Against visceral Leishmaniasis in Non-Human Primate Model: Use of high potential Adjuvants.
  • Prof. M. Gicheru, Dr. J. Mutiso, Dr. E. Kairu, Dr. D. Muia, Ms. L. Kavinda (2015) Effects of lake baringo flooding on human health and livelihoods of the surrounding communities.
  • Prof. M. Gicheru, Dr. J. Mutiso, Dr. B. Mwangi, Dr. D. Muia, Ms. L. Kavinda (2014-2016) Establishing the impact of extreme flooding of Lake Baringo on livestock and fisheries productivity and the farming community living around the lake

 

 

 

Last Updated on Tuesday, 10 November 2015 05:21

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