Dr. Alex King’ori Machocho

Machocho  

Department of Chemistry
Kenyatta University
P.O Box 43844 – (00100 GPO)
Nairobi
Tel: (254) (020) 8710901 ext. 57455
Cellphone: (+254) 722 252877
E-mail addresses: This email address is being protected from spambots. You need JavaScript enabled to view it. or This email address is being protected from spambots. You need JavaScript enabled to view it.

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Publications/Journal Articles

  1. Mwangi, E.S.K., Keriko, J.M., Machocho, A.K., Wanyonyi, A.W., Malebo, H.M., Chhabra, S.C. and Tarus, P.K. (2010). Antiprotozoal Activity and Cytotoxicity of metabolites from keaves of Teclea trichocarpa. Journal of Mecinal Plants Research 4 (9): 726-731.
  2. Ruttoh, E.K., Bii, C.C., Tarus, P.K., Machocho, A.K., Karimi, L.K. and Okemo, P.O. (2009) Antifangal Activity of Tabernaemontana stapfiana Britten (Apocynaceae) Organic Extracts. Pharmacognosy Research 1 (6): 387-391.
  3. Ruttoh, E.K., Tarus, P.K., Bii, C.C., Machocho, A.K., Karimi, L.K. and Okemo, P.O. (2009) Antibacterial Activity of Tabernaemontana stapfiana Britten (Apocynaceae) Extracts. Afr. J. Trad. CAM 6 (2): 186-194.
  4. Kirira, P.G., Rukunga, G.M., Wanyonyi, A.W., Muthaura, C.N., Geoffrey M. Mungai, G.M., Machocho, A.K. and Isaiah O. Ndiege, I.O. (2007) Tigliane Diterpenoids from the Stem Bark of Neoboutonia macrocalyx, Journal of. Natural Products 70 (5), 842-845.
  5. Machocho, A.K., Chhabra, S.C., Codina, C., Viladomat, F., Bastida, J. (2005) Amaryllidaceae Alkaloids from Crinum kirkii Baker. Proceedings, Kenya Chemical Society International Conference; Kenyatta University, August, 2005).
  6. Mwangi, E.K., Machocho, A.K., Tarus, P.K., Keriko, J.M., Chhabra, S.C., Wanyonyi. A.W. and Malebo, H.M. (2005). Phytochemical and Biological Studies of Teclea trichocarpa and Albizia anthelmintica. Proceedings, Kenya Chemical Society International Conference; Kenyatta University, August 2005)
  7. Machocho, A.K., Bastida, J., Codina, C., Viladomat, F., Brun, R. and Chhabra, S.C. (2004) Augustamine type alkaloids from Crinum kirkii, Phytochemistry 65 (23), 3143-3149.
  8. Machocho, A.K., Win, T., Grinberg, S. and Bittner, S. (2003) Reactions of benzoquinones and naphthaquinones with 1,8-diamino-3,6-dioxanonane and with 1,11-diamino-3,6,9-trioxaundecane. Tetrahedron Letters 44 (29), 5531-5534.
  9. Machocho, A.K., Kiprono, P.C., Grinberg, S. and Bittner, S. (2003) Pentacyclic triterpenoids from Embelia schimperi. Phytochemistry 62 (4), 573-577.
  10. Tarus, P.K., Machocho, A.K., Lang’at, C.C. and Chhabra, S.C. (2002) Flavonoids from Tephrosia aequilata, Phytochemistry, 60, 375-379.
  11. Labranya, J., Machocho, A.K., Kricsfalusy, V., Brun, R., Codina, C., Viladomat, F., Bastida, J. (2002) Alkaloids from Narcissus angustifolius subsp. transcarpathicus (Amaryllidaceae). Phytochemistry 60, 847-852.
  12. Herrera, M.R., Machocho, A.K., Nair, J.J., Campbell, W.E., Brun, R., Viladomat, F., Codina, C. and Bastida, J. (2001) Alkaloids from Cyrtanthus elatus, Fitoterapia 72, 444-448.
  13. Herrera, M.R., Machocho, A.K., Brun, R., Viladomat, F., Codina, C. and Bastida, J. (2001) Alkaloids from Zephyranthes citrina Baker, Planta Medica 67, 191-193.
  14. Nair, J.J., Machocho, A.K., Campbell, W.E., Brun, R., Viladomat, F., Codina, C. and Bastida, J. (2000) Alkaloids from Crinum macowanii, Phytochemistry 54, 945-950.
  15. Machocho, A., Chhabra, S.C., Viladomat, F., Codina, C. and Bastida, J. (1999) Alkaloids from Ammocharis tinneana, Phytochemistry, 51 1185-1191.
  16. Machocho, A., Chhabra, S.C., Viladomat, F., Codina, C. and Bastida, J. (1998) Alkaloids from Crinum stuhlmannii, Planta Medica, 64 679-680.
  17. Machocho, A.K., Lwande, W., Jondiko, J.O., Moreka, L.V.C. and Hassanali, A. (1995) Three new flavonoids from the roots of Tephrosia emoroides and their antifeeding activity against the Larvae of the Spotted Stalk Borer Chilo partellus Swinhoe; International Journal of Pharmacognosy 33 (3), 222-227.
  18. Global Journal of Science Frontier Research: B Chemistry Volume 14 Issue 4 Version 1.0 Year 2014 Type : Double Blind Peer Reviewed International Research Journal Publisher: Global Journals Inc. (USA) Online ISSN: 2249-4626 & Print ISSN: 0975-5896
    Efficacy and Safety Assessment of Launaea cornuta Extracts in the Management of Diabetes Mellitus

  19. US-Africa Collaboration in a Chemical Education Project Involving Analysis of Amaranthus Grain Oil from Selected Agro-Ecological Zones in Kenya
  20. Biflavonoids from an Ethno-Medicinal Plant Ochna holtzii Gilg
  21. A Quantitative Analytical Chemistry Research-based Experiment Involving Comparative Analysis of Amaranth Grain Oils Extracted from Embu and Meru Districts in Kenya
  22. Journal of Kenya Chemical Society Vol. 8: Issue 1, 2014
  23. PROFILING OF THE CHEMICAL COMPOUNDS IN ETHYL ACETATE EXTRACTS OF LAUNAEA CORNUTA ASTERACEAE BY GC-MS
  24. Bisbenzylisoquinoline and hasubanane alkaloids from Stephania abyssinica (Dillon & A. Rich) (Menispermeceae)
  25. The role of phytomedicine in the challenges of emerging, re-emerging diseases; and pathogens resistance to antibiotics
  26. Profiling of antimicrobial properties of Rubus keniensis Standl. Crude methanol root bark extracts against selected human pathogenic bacteria
CONFERENCES/SEMINARS/WORKSHOPS (PRESENTATIONS)
  1. International Nanomedicine Workshop on Infectious Diseases of Poverty: Perspectives and Possibilities. Magaliesberg South Africa. 27th to 31st March 2011.
  2. Formulation of Bioprospecting Strategy Framework for Protected Areas for KWS, Whitesands Hotel. Mombasa 27th Feb to 3rd March 2011
  3. Regional Consultative Workshop on “Enhancing the Conservation and Use of Neglected and Underutilized Species of Crops in Eastern & Southern Africa”. Kenyatta University Conference Centre. 26th -28th July 2010.
  4. Capacity Building Working on Interpretation and Domestication of the Universal Declaration on Bioethics and Human Rights. KNATCOM-UNESCO. Multimedia University College 25th to 28th May 2010.
  5. Bioprospecting Experts Workshop for KWS. Voi Safari Lodge Tsavo Park 20th -25th June 2010.
  6. Intellectual Property Workshop for Researchers in Nairobi Region by KIPI. Lukenya Getaway Hotel: 24th -27th February 2010.
  7. Pan-African Green Chemistry Workshop. Cape Town, South Africa on 24th -26th Jan 2007.
  8. Lake Victoria Research Initiative (VICRES) - SIDA/SAREC/IUCEA. Various workshops and seminars within the regions since 2004 to present and on going.
  9. Amaryllidaceae alkaloids from Crinum kirkii Kenya Chemical Society Conference, August 2005, Kenyatta University, Nairobi.
  10. Phytochemical and Biological Studies of Teclea trichocarpa and Albizia anthelmintica. Proceedings, Kenya Chemical Society International Conference; Kenyatta University, August 2005)
  11. New pentacyclic triterpenoids from Embelia schimperi. Israel Chemical Society Meeting 29-30 January, 2002, Jerusalem.
  12. Natural quinones and pentacyclic triterpenoids from Myrsinaceae. Faculty of Pharmacy, University of Barcelona as a visiting researcher in Natural Products Chemistry. 9-14 January, 2002, Barcelona.
  13. A Pterocarpan and Chalcones from Tephrosia aequilata The 9th Symposium of The Natural Product Research Network for Eastern and Central Africa (NAPRECA), OP-30 (p.29), 27-31 August, 2001, Nairobi.
  14. The 9th Symposium of The Natural Product Research Network for Eastern and Central Africa (NAPRECA), OP-55 (p 56), 27-31 August, 2001, Nairobi.
  15. Isolation and characterization of bioactive flavonoids from Tephrosia aequilata presented to the NAPRECA conference in Kenyatta International Conference Centre, Nairobi, Kenya. 27th - 31st August 2001.
  16. Natural Products Research of Eastern and Southern Africa (NAPRECA) Kenya Chapter symposium on 26th January, 2001 at Kenyatta University.
  17. Alkaloids from Narcissus angustifolius subsp. transcarpathicus (Amaryllidaceae), 48th Annual Meeting of the Society for Medicinal Plant Research (GA), Natural Products Research in the New Millenium. 3-7 Sept 2000, Zurich.
  18. An acethylcholinesterase inhibiting alkaloid fron the South African Cyrtanthus sanguineus  48th Annual Meeting of the Society for Medicinal Plant Research (GA), Natural Products Research in the New Millenium. 3-7 Sept 2000, Zurich.
  19. Alkaloids from Kenyan Amaryllidaceae. Medicinal Plants, Traditional Medicines and Local Communities in Africa: Challenges and Opportunities of the next Millenium, 16-19 May 2000, Nairobi, Kenya.
  20. Biological Assays in Natural Products Research. University of Barcelona, Spain, 25–29 Jan. 1999.
  21. Alkaloids from Zephyranthes citrina Baker, 16 Conferencia de Quimica, 1999, Santiago de Cuba, QO-P 75.
  22. Alkaloids from Ammocharis tinneana, 46th Annual Congress of the Society for Medicinal Plant, Research, 1998, Vienna, Austria, G-04.
  23. Biological Assays in Natural Products Research. University of Barcelona, Spain; 26th–30th Jan. 1998.

 

 

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