Name: Dr. Wycliffe Arika Makori.
Qualification: PhD
Position :Lecturer
Department: Biochemistry, Microbiology and Biotechnology
Address: P.O. Box 43844, 00100,Nairobi, Kenya
Email: This email address is being protected from spambots. You need JavaScript enabled to view it. 
Area of Specialization: Medical Biochemistry and Medical Oncology
Research Interests: Diabetes Mellitus, Obesity, Neurodegenerative disorders (Cognitive impairments and spontaneously emitted behaviors viz. locomotor activity, anxiety and exploration) and Medical Oncology (Cancer).
ORCID: https://orcid.org/0000-0002-6928-4158 
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PUBLICATIONS                                                                                                                                                     

Corresponding Author Publications:

  • Arika, W.M., Kibiti, C.M., Njagi, J.M., & Ngugi, M.P. (2019). Anti˗Obesity Effects of Dichloromethane Leaf Extract of Gnidia glauca in High Fat Diet-Induced Obese Rats. Heliyon, 5: 1˗15. doi.org/10.1016/j.heliyon. 2019.e02800.
  • Arika, W.M, Kibiti, C.M., Njagi, J.M., & Ngugi, M.P. (2019). In Vitro Antioxidant Properties of Dichloromethanolic Leaf Extract of Gnidia glauca (Fresen) as a Promising Antiobesity Drug. Journal of Evidence-Based Integrative Medicine, 24:1˗17. doi.org/10.1177/2515690X19883258.
  • Arika, W.M., Kibiti, C.M., Njagi, J.M., & Ngugi, M.P. (2019). Modulation of Cognition: The Role of Gnidia glauca on Spatial Learning and Memory Retention in High-Fat Diet-Induced Obese Rats. Neural plasticity, 2019: 1˗16. doi.org/10.1155/2019/2867058.
  • Arika, W.M., Kibiti, C.M., Njagi, J.M., & Ngugi, M.P. (2019). Effects of DCM Leaf Extract of Gnidia glauca (Fresen) on Locomotor Activity, Anxiety, and Exploration˗Like Behaviors in High˗Fat Diet-Induced Obese Rats. Behavioural Neurology, 2019: 1˗14. doi.org/10.1155/2019/7359235.
  • Arika, W.M., Nyamai, D.W., Musila, M.N., Ngugi, M.P., Njagi, E.N.M (2016). Hematological Markers of in Vivo Toxicity. Journal of Hematology and Thromboembolic Diseases, 4: 236. doi:10.4172/2329˗8790.1000236.
  • Arika, W.M., Nyamai., D.W., Osano, K.O., Ngugi, M.P., Njagi, E.N.M (2016). Biochemical Markers of in Vivo Hepatotoxicity. Journal of Clinical Toxicology, 6: 297.doi:10.4172/2161˗0495.1000297.
  • Arika, W.M., Nyamai, D.W., Agyirifo, D.S., Ngug, M.P., Njagi, E.N.M. (2016). In Vivo Antidiabetic Effect of Aqueous Leaf Extract of Azardirachta indica, A. Juss in Alloxan Induced Diabetic Mice. Journal of Diabetic Complications and Medicine, 1: 106. doi:10.4172/jdcm.1000.106.
  • Arika, W.M., Ogola, P.E., Nyamai, D.W., Mawia, A.M., Wambua, F.K., et al. (2016). Mineral Elements Content of Selected Kenyan Antidiabetic Medicinal Plants. Advanced Techniques in Biology and Medicine, 4: 160. doi: 10.4172/2379˗1764.1000160.
  • Arika, W.M., Rachuonyo, H.O., Muchori, A.N., Lagat, R.C., Mawia, A.M., et al. (2016) Hypoglycemic Effect of Ocimum Lamiifolium in Alloxan Induced Diabetic Mice. Med Aromat Plants 5: 228. doi:10.4172/2167-0412.1000228
  • Arika, W.M., Abdirahman, Y.A., Mawia, M.A. et al. (2015). In Vivo Antidiabetic Activity of the Aqueous Leaf Extract of Croton macrostachyus in Alloxan Induced Diabetic Mice. Pharmaceutica Analytica Acta, 6: 447. doi: 10.4172/21532435.1000447.
  • Arika, W.M., Abdirahman, Y.A., Ogola, P.E., Kiboi, N.G., Njagi, S.M., et al. (2015). Hypoglycemic Effect of Lippia javanica in Alloxan Induced Diabetic Mice. Journal of Diabetes and Metabolism, 6: 624. doi:10.4172/2155˗6156.1000624.
  • Arika, W.M., Ogola, P.E., Abdirahman, Y.A., Mawia, A.M., Wambua, F.K., Nyamai, D.W., et al. (2015). In Vivo Safety of Aqueous Leaf Extract of Lippia javanica in Mice Models. Journal of Physiology and Biochemistry, 5: 191. doi: 10.4172/2168˗9652.1000191.

Other Joint Publications:

  • A Pre-print: Junnan Liu, Xue Wang, Anca Azoitei, Tim Eiseler, Sabine Meessen, Wencheng Jiang, Xi Zheng, Arika W. Makori, Christian Bolenz …. & Cagatay Günes. (2023) "Novel ploidy-control genes ORP3 and GJB3 link aneuploidy to tumor cell invasion through microtubule and actin dynamics"
  • Xu, P., Richter, J., Blatz, A., Gärtner, F., Alberts, R., Azoitei, A., Makori, W.A., ... & Günes, C. (2020). Downregulation of ORP3 Correlates with Reduced Survival of Colon Cancer Patients with Advanced Nodal Metastasis and of Female Patients with Grade 3 Colon Cancer. International Journal of Molecular Sciences, 21: 5894.
  • Ruth, K.M., Warutere, P.N., Nyamari, J., & Arika, W. (2020). Levels of Ionizing Radiations in Selected Quarries in Nyamira County, Kenya. Heliyon, 6: e04363.
  • Njogu, S.M., Arika, W.M., Machocho, A.K., Ngeranwa, J.J., & Njagi, E.N. (2018). In Vivo Hypoglycemic Effect of Kigelia africana (Lam): Studies with Alloxan-Induced Diabetic Mice. Journal of Evidence-Based Integrative Medicine, 23: 1˗10. doi.org/10.1177/2515690.
  • Ouko, R.O., Koech, S.C., Arika, W.M., Njagi, S.M., & Oduor, R.O. (2017). Bioefficacy of Organic Extracts of Ocimum basilicum against Sitophilus zeamais. Entomology, Ornithology and Herpetology, 6: 1˗7. doi: 10.4172/2161˗0983.1000190.
  • Stephen, N.M., Wycliffe, A.M., Alex, M.K., Joseph, N.J., & Eliud, N.N. (2017). In vivo antidiabetic activity of aqueous and ethyl acetate leaf extract of Senna singuena (Delile) in alloxan induced diabetic mice. The Journal of Phytopharmacology, 6: 84˗92. X 18768727.
  • Nyamai, D.W., Arika, W.M., Ogola, P.E., Njagi, E.N.M., Ngugi, M.P. (2016). Medicinally Important Phytochemicals: An Untapped Research Avenue. Journal of Pharmacognosy and Phytochemistry, 4: 35˗49. e˗ISSN:2321˗6182.
  • Ogola, P.E., Arika, W.M., Nyamai, D.W., Osano, K.O., & Rachuonyo, H.O. (2016). Determination of Background Ionizing Radiations in Selected Buildings in Nairobi County, Kenya. Journal of Nuclear Medicine and Radiation Therapy, 7: 2. doi:10.4172/2155˗-9619.1000289.
  • Nyamai, D.W., Arika, W.M., Rachuonyo, H.O., Wambani, J.R., & Ngugi, M.P. (2016). Herbal Management of Benign Prostatic Hyperplasia. Journal of Cancer Science and Therapy, 8: 130˗134. doi:10.4172/1948˗5956.1000404.
  • Muruthi, C.W., Lwande, O.W., Makumi, J.N., Runo, S., Otiende, M., & Makori, W.A. (2016). Phenotypic and Genotypic Identification of Ticks Sampled from Wildlife Species in Selected Conservation Sites of Kenya. Journal of Veterinary Science and Technology, 7: 2. doi:10.4172/2157-7579.1000293.

CONFERENCE PRESENTATIONS                                                                                                        

Presentation of Papers at International Seminars and Conferences

  • 4th April, 2020. International Seminars on “Role of Research in Management of Bladder Cancer”
    Paper Presented:“Loss of ORP3 Induces Genome Instability and Cancer” held in the Institute for Clinical Transfusion Medicine and Immunogenetics, Ulm, Germany.

Participation in International Conferences, Seminars and Workshops

  • 18th May 2022: Attended a virtual workshop to sensitize teaching members of staff on the new research information system(KENRIS) and science, Technology and Innovation(STI) mainstreaming by the National Commission for Science Technology and Innovation. The workshop aimed at improving efficiency and integrating KU teaching staff into national and global research tracking systems.
  • 28th of May, 2021: Attended Global Research Ethics Workshop for University-based Researchers in Africa.
  • The Global Research Ethics Project is a multidisciplinary collaboration between researchers from across the world to develop practical tools and guides to navigate the ethical dilemmas that can arise in global challenges research.
  • 16th August, 2019. Attended Workshop on “Early detection of the Bladder cancer and Initiatives for better implementation of clinical studies in urology”, Co-hosted by the Clinics of Urology at the University Hospital and Bundeswehr Hospital Ulm, Germany.
  • 24th – 26th August, 2016. Attended 4th International Annual Scientific Conference of the Society for the Advancement of Science in Africa (SASA) at Kenyatta University, Kenya.
  • 31st November, 2015 ˗ 4th December, 2015. Attended the 31st postgraduate seminar at Kenyatta University. Theme: Supporting the Economy through Research.

SEMINARS                                                                                                                                              

  • Attended and participated in a seminar on Enhancing Coordination, Collaboration and Partnerships for Effective Implementation of Biosafety Regulations held at Kenya School of Monetary Studies organized and facilitated by National Biosafety Authority, 11th-15th August 2015.
  • Attended and participated in a seminar on Transformative Leadership Skills held at Kenyatta   University Student’s Business Centre organized by Kenyatta University Mentoring Programme, 10th -13th December 2012.
  • Attended a public lecture at Kenyatta University AVU Hall on Emerging Viruses-Arbovirus, rotavirus, H1N1 and Virus detection techniques organized by KUBIOC and facilitated by KEMRI/WRP, 10th October 2009

COMMUNITY OUTREACH                                                                                                                      

  • September 2021-To date: Patron, Kenyatta University Biochemistry and Biotechnology Student Association
  • Routine delivery of motivation talks to high school students and societal youths through ‘Tufaane Initiative’ of ‘Gofar Africa’.
  • Organized and successfully coordinated celebrations of World Diabetes Day, 2014 in conjunction with KUSA and Directorate of University Health Services at Kenyatta University.
  • Carrying out HIV/AIDS, Non-Communicable Diseases as well as Drugs and Substance abuse awareness and campaigns.
  • Providing information relating with the use contraceptives to students and the university community.

MEDIA                                                                                                                                                          

  • Featured in the Standard News Paper: Emerging Alternative Remedies for Obesity and Associated Metabolic Complications: In Vitro Antioxidant Properties of Dichloromethanolic Leaf Extract of Gnidia glauca (Fresen) as a Promising Antiobesity Drug on 10th October, 2019.

ACHIEVEMENTS                                                                                                                                       

  • Optimization of experimental models for induction of Obesity, Diabetes, Dementia, and Anxiety in laboratory animal models
  • Participatory and collaborative development of curricula for Bachelors of Pharmacy at South Eastern Kenya University (SEKU)